Sunday, January 27, 2013

Endocrine Disruptor: Methoxychlor


Methoxychlor



Methoxychlor is used as an insecticide effective against pests. There’s a wide range of uses of methoxychlor, from being used on field crops to killing parasites. However, all pesticide use of methoxychlor was suspended in 2000. According to oral study in animals, the exposure of methoxychlor resulted in effects to the liver, kidneys, and nervous system. Moreover, the reproductive and developmental effects are the major concern of methoxychlor. Developmental and reproductive effects include abortions, reduced fertility, reduced litter size, and skeletal effects. The exposure to methoxychlor would most likely be from inhalation or dermal contact by workers involved in the manufacture, handling, or application of methoxychlor. Humans could be exposed to methoxychlor at home by ingesting food or water contaminated with methoxychlor. EPA has low confidence in the dangerous study of methoxychlor because no inferences could be made to the maternal or developmental toxicity of methoxychlor due to the low sureness in the database because of the lack of definitive chronic toxicity. EPA has classified methoxychlor as a Group D, because human data are unavailable and animal evidence is indecisive.

No comments:

Post a Comment